This is probably a mistake, but I'm not scared of you. Lixis often has the advantage in clashes when the opponent has less bases than she does, Lance prevents Dreamscape from being a guaranteed melee hit, Mirage would only make it less likely for me to be outsped half the time, and Pruning could theoretically get to 9 priority against it without spending force, and Naturalizing eats tokens while generally doing 2 damage, so you don't get it back. I think the only matchup advantage you have is that Lixis is going to have a hard time getting around Blind.
That is, assuming I'm reading the interactions correctly. Even then, none of this is actually going to stop me from just getting outplayed, which has been the case for a majority of these games.